​Pharmaceutical Centralized Clean-In-Place (CIP) Systems

Boehringer Ingelheim Skid

In similar fashion to pharmaceutical facilities, animal health facilities are a highly regulated and monitored business. These facilities adhere to the same guidelines as a pharmaceutical facility, and in many ways, the differences between the two are blurred at best.

Central States Industrial (CSI) was approached by an engineering firm to provide clean-in-place (CIP) systems for a large greenfield (previously undeveloped) animal health facility. These CIP systems required fabrication practices that followed Current Good Manufacturing Practice (cGMP) and American Society of Mechanical Engineers: Bioprocessing Equipment (ASME-BPE) standards.

CSI engineers and project managers took the customer supplied process and instrumentation diagram (P&ID) and created three identical fully functional CIP systems complete with controls and platforms. Each skid had three 900 liter vessels and a pump to provide 50 gpm and 82 psig. The systems were built to the desired specifications, on time and on budget.


Central States Industrial Equipment (CSI) is a leader in distribution of hygienic pipe, valves, fittings, pumps, heat exchangers, and MRO supplies for hygienic industrial processors, with four distribution facilities across the U.S. CSI also provides detail design and execution for hygienic process systems in the food, dairy, beverage, pharmaceutical, biotechnology, and personal care industries. Specializing in process piping, system start-ups, and cleaning systems, CSI leverages technology, intellectual property, and industry expertise to deliver solutions to processing problems. More information can be found at www.csidesigns.com.